First-line therapies
- AHA/ACC 2017: thiazide diuretics, CCBs, and ARBs (IA recommendation)
- Recommend dual therapy with fixed-dose combo if Stage 2 HTN (i.e., SBP ≥ 140 or DBP ≥ 90) and an average BP > 20/10 mmHg above BP target (IA)

- ESC/ESH 2018
Second-line therapies


